Targeting MELK in tumor cells and tumor microenvironment: from function and mechanism to therapeutic application-Reference-Cited by-同舟云学术

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Targeting MELK in tumor cells and tumor microenvironment: from function and mechanism to therapeutic application

Published:2024-08-26 Issue: Volume: Page:
ISSN:1699-3055
Container-title:Clinical and Translational Oncology
language:en
Short-container-title:Clin Transl Oncol

Author:

Su Pengfei,Lu Qiliang,Wang Yuanyu,Mou Yiping,Jin Weiwei^ORCID

Funder

Key Medical Science and Technology Project of Zhejiang Province

Key Projects of Zhejiang Provincial Science and Technology

Zhejiang Provincial Science and Technology Program of Traditional Chinese Medicine

Zhejiang Provincial Medical and Health Technology Program

Key Project of Laboratory Research in Hangzhou Medical College

Publisher

Springer Science and Business Media LLC

Link

https://link.springer.com/content/pdf/10.1007/s12094-024-03664-5.pdf

Reference88 articles.

1. Tang Q, Li W, Zheng XJ, Ren LW, Liu JY, Li S, et al. MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma. Signal Transduct Target Ther. 2020;5(1):279.

2. Liu HL, Sun QW, Sun YL, Zhang JP, Yuan HY, Pang SH, et al. MELK and EZH2 cooperate to regulate medulloblastoma cancer stem-like cell proliferation and differentiation. Mol Cancer Res. 2017;15(9):1275–86.

3. Thangaraj K, Ponnusamy L, Natarajan SR, Manohara R. MELK/MPK38 in cancer: from mechanistic aspects to therapeutic strategies. Drug Discov Today. 2020;25(12):2161–73.

4. Ganguly R, Mohyeldin A, Thiel J, Kornblum HI, Beullens M, Nakano I. MELK-a conserved kinase: functions, signaling, cancer, and controversy. Clin Transl Med. 2015;4:11.

5. Li ZP, Zhou HX, Zhai XY, Gao L, Yang MF, An BK, et al. MELK promotes HCC carcinogenesis through modulating cuproptosis-related gene DLAT-mediated mitochondrial function. Cell Death Dis. 2023;14(11):733.

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