Metabolic activation of chlorinated ethylenes: dependence of mutagenic effect on electrophilic reactivity of the metabolically formed epoxides
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00343270.pdf
Reference14 articles.
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3. Bonse, G., Urban, Th., Reichert, D., Henschler, D.: Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation. Biochem. Pharmacol. 24, 1829 (1975)
4. Butler, T. C.: Metabolic transformation of Tri. J. Pharmacol. Exp. Ther. 97, 84 (1949)
5. Daniel, J. W.: The metabolism of 36Cl-labelled trichloroethylene and tetrachloroethylene in the rat. Biochem. Pharmacol. 12, 795 (1963)
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