Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms-Reference-Cited by-同舟云学术

Correlation of inter-individual variations of amitriptyline metabolism examined in hairs with CYP2C19 and CYP2D6 polymorphisms

Published:2007-11-09 Issue:2 Volume:122 Page:149-155
ISSN:0937-9827
Container-title:International Journal of Legal Medicine
language:en
Short-container-title:Int J Legal Med

Author:

Thieme Detlef,Rolf Burkhard,Sachs Hans,Schmid Dagmar

Publisher

Springer Science and Business Media LLC

Subject

Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00414-007-0184-4.pdf

Reference23 articles.

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3. van der Weide J, van Baalen-Benedek EH, Kootstra-Ros JE (2005) Metabolic ratios of psychotropics as indication of cytochrome P450 2D6/2C19 genotype. Ther Drug Monit 27:478–483

4. Oleson O, Linnet K (1997) Hydroxylation and demethylation of the tricyclic antidepressant nortriptyline by cDNA-expressed human cytochrome P-450 isoenzymes. Drug Metab Dispos 25:740–744

5. Steimer W, Zopf K, von Amelunxen S et al (2004) Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers. Clin Chem 50:1623–1633

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