Covalent arylation of metallothionein by oxidized dopamine products: A possible mechanism for zinc-mediated enhancement of dopaminergic neuron survival

Author:

Gauthier Michelle A.,Eibl Joseph K.,Crispo James A. G.,Ross Gregory M.

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Reference39 articles.

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2. Andrews GK (2000) Regulation of metallothionein gene expression by oxidative stress and metal ions.Biochem. Pharmacol. 59(1), 95–104.

3. Asanuma M, Miyazaki I, Higashi Y, Tanaka K, Haque ME, Fujita N and Ogawa N (2002) Aggravation of 6-hydroxydo-pamine-induced dopaminergic lesions in metallothionein-I and -II knock-out mouse brain.Neurosci. Lett. 327(1), 61–65.

4. Aschner M (1998) Metallothionein (MT) isoforms in the central nervous system (CNS): regional and cell-specific distribution and potential functions as an antioxidant.Neurotoxicology 19(4-5), 653–660.

5. Aschner M, Cherian MG, Klaassen CD, Palmiter RD, Erickson JC and Bush AI (1997) Metallothioneins in brain - the role in physiology and pathology.Toxicol. Appl. Pharmacol. 142(2), 229–642.

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