Feasible model for locoregional and systemic longterm administration of drugs and concomitant blood sampling in Sprague-Dawley rats

Author:

Aguiar J. L.,Bartkowski R.,Berger M. R.,Petru E.,Schlag P.,Schm�hl D.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference13 articles.

1. Aguiar JL (1986) Pharmacokinetics and toxicity of 5-fluorouracil in experimental thioacetamide-induced cirrhosis after intraarterial liver administration to rats. Inauguraldissertation der Medizinischen Gesamtfakultät, Unieersität Heidelberg

2. Aigner K, Walther H, Tonn J, Wenzl A, Hechtel R, Merker G, Schwemmle K (1983) First experimental and clinical results of isolated liver perfusion with cytotoxics in metastases from colorectal primary. Recent Results Cancer Res 86:88?102

3. Ansfield FJ, Ramirez G (1978) The clinical results of 5-fluorouracil intrahepatic arterial infusion in 528 patients with metastatic cancer to the liver. Prog Clin Cancer 7:201?206

4. Bartkowski R, Berger MR, Aguiar JL, Henne T, Dörsam J, Geelhaar G, Schlag P, Herfarth C (1986) Experiments on the efficacy and toxicity of locoregional chemotherapy of liver tumors with 5-fluoro-2-deoxyuridine (FUDR) and 5-fluorouracil (5-FU) in an animal model. J Cancer Res Clin Oncol 111:42?46

5. Chen HS, Gross JF (1980) Intra-arterial infusion of anticancer drugs: theoretic aspects of drug delivery and review of reponse. Cancer Treat Rep 64:31?40

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