Interaction of cimetidine with the triazolobenzodiazepines alprazolam and triazolam

Author:

Abernethy Darrell R.,Greenblatt David J.,Divoll Divoll,Moschitto Lawrence J.,Harmatz Jerold S.,Shader Richard I.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference19 articles.

1. Abernethy DR, Greenblatt DJ, Divoll M, Ameer B, Shader RI (1983) Differential effect of cimetidine on drug oxidation (antipyrine, diazepam) versus conjugation (acetaminophen, lorazepam): Prevention of acetaminophen toxicity by cimetidine. J Pharmacol Exp Ther 224:508?513

2. Cohn JB (1981) Multicenter double-blind efficacy and safety study comparing alprazolam, diazepam, and placebo in clinically anxious patients. J Clin Psychiatry 42:347?351

3. Desmond PV, Patwardhan RV, Schenker S, Speeg KV (1980) Cimetidine impairs elimination of chlordiazepoxide (Librium) in man. Ann Int Med 93:266?268

4. Divoll M, Greenblatt DJ, Abernethy DR, Shader RI (1982) Cimetidine impairs clearance of antipyrine and desmethyldiazepam in the elderly. J Am Geriatr Soc 30:684?689

5. Eberts FS, Philopoulos Y, Reineke LM, Vliek RW (1980) Disposition of 14C-alprazolam, a new anxiolytic-antidepressant, in man (abstract). Pharmacologist 22:279

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