Interaction of vasoactive intestinal peptide with rat small intestinal epithelial cells after intestinal resection-Reference-Cited by-同舟云学术

Interaction of vasoactive intestinal peptide with rat small intestinal epithelial cells after intestinal resection

Published:1985-07-01 Issue:7 Volume:5 Page:559-566
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Diaz-Juarez José L.¹,Bodega Guillermo²,Arilla Eduardo¹,Prieto Juan C.¹

Affiliation:

1. Departamento de Bioquímica, Facultad de Medicina, Universidad de Alacalá de Henares, Madrid, Spain

2. Departamento de Histología, Facultad de Ciencias, Universidad de Alacalé de Henares, Madrid, Spain

Abstract

Specific binding of vasoactive intestinal peptide (VIP) and VIP-stimulated cyclic AMP accumulation were studied in small intestinal epithelial cells (both of crypt and villous levels) 3, 7 and 14 d after a 60% resection of the small intestine. The affinity, but not the binding capacity, of VIP receptors decreased during the adaptive hyperplastic response. Basal cyclic AMP levels were similar in cells of both control and resected rats. Resection induced a decrease of potency, but not of efficiency, of VIP on the stimulation of cyclic AMP accumulation.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/5/7/559/519666/bsr0050559.pdf

Reference22 articles.

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3. Dowling RH (1982) Scand. J. Gastroenterol.17 (Suppl. 74), 53?74.

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