An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease-Reference-Cited by-同舟云学术

An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease

Published:2018-03-27 Issue:6 Volume:135 Page:827-837
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

De Roeck Arne, ,Duchateau Lena,Van Dongen Jasper,Cacace Rita,Bjerke Maria,Van den Bossche Tobi,Cras Patrick,Vandenberghe Rik,De Deyn Peter P.,Engelborghs Sebastiaan,Van Broeckhoven Christine,Sleegers Kristel^ORCID

Funder

Alzheimer Research Foundation

Belgian Science Policy Interuniversity Attraction Poles Program

Flemish government-initiated Flanders Impulse Program on Networks for Dementia Research

Flemish government-initiated Methusalem Excellence Program

VIB Technology Fund

Fonds Wetenschappelijk Onderzoek

Rotary Belgium

Bijzonder Onderzoeksfonds

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Link

http://link.springer.com/article/10.1007/s00401-018-1841-z/fulltext.html

Reference54 articles.

1. 1000 Genomes Project Consortium, Auton A, Brooks LD, Durbin RM, Garrison EP, Kang HM et al (2015) A global reference for human genetic variation. Nature 526:68–74. https://doi.org/10.1038/nature15393

2. Allen M, Lincoln SJ, Corda M, Watzlawik JO, Carrasquillo MM, Reddy JS et al (2017) ABCA7 loss-of-function variants, expression, and neurologic disease risk. Neurol Genet 3:e126. https://doi.org/10.1212/NXG.0000000000000126

3. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS et al (2012) Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology 79:221–228. https://doi.org/10.1212/WNL.0b013e3182605801

4. Bamji-Mirza M, Li Y, Najem D, Liu QY, Walker D, Lue L-F et al (2016) Genetic variations in ABCA7 can increase secreted levels of amyloid-β40 and amyloid-β42 peptides and ABCA7 transcription in cell culture models. J Alzheimer’s Dis 53:875–892. https://doi.org/10.3233/JAD-150965

5. Bates D, Mächler M, Bolker B, Walker S (2015) Fitting linear mixed-effects models using lme4. J Stat Softw. https://doi.org/10.18637/jss.v067.i01

Cited by 74 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Very low levels of ABCA7 in the cerebrum and Alzheimer’s disease onset between the ages of 60 and 80 independently of APOE;Journal of Neuropathology & Experimental Neurology;2024-06-20

2. Emerging Role of ABC Transporters in Glia Cells in Health and Diseases of the Central Nervous System;Cells;2024-04-24

3. Toward understanding the role of genomic repeat elements in neurodegenerative diseases;Neural Regeneration Research;2024-04-16

4. The ABC's of Alzheimer risk gene ABCA7;Alzheimer's & Dementia;2024-03-31

5. Nanopore-based DNA long-read sequencing analysis of the aged human brain;2024-02-05