Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress-Reference-Cited by-同舟云学术

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

Published:2014-08-31 Issue:4 Volume:128 Page:505-524
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

Zhang Yong-Jie,Jansen-West Karen,Xu Ya-Fei,Gendron Tania F.,Bieniek Kevin F.,Lin Wen-Lang,Sasaguri Hiroki,Caulfield Thomas,Hubbard Jaime,Daughrity Lillian,Chew Jeannie,Belzil Veronique V.,Prudencio Mercedes,Stankowski Jeannette N.,Castanedes-Casey Monica,Whitelaw Ena,Ash Peter E. A.,DeTure Michael,Rademakers Rosa,Boylan Kevin B.,Dickson Dennis W.,Petrucelli Leonard

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Link

http://link.springer.com/article/10.1007/s00401-014-1336-5/fulltext.html

Reference78 articles.

1. Abasolo N, Torrell H, Roig B, Moyano S, Vilella E, Martorell L (2011) RT-qPCR study on post-mortem brain samples from patients with major psychiatric disorders: reference genes and specimen characteristics. J Psychiatr Res 45(11):1411–1418. doi: 10.1016/j.jpsychires.2011.06.001

2. Al-Sarraj S, King A, Troakes C, Smith B, Maekawa S, Bodi I, Rogelj B, Al-Chalabi A, Hortobagyi T, Shaw CE (2011) p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS. Acta Neuropathol 122(6):691–702. doi: 10.1007/s00401-011-0911-2

3. Ash PE, Bieniek KF, Gendron TF, Caulfield T, Lin WL, Dejesus-Hernandez M, van Blitterswijk MM, Jansen-West K, Paul JW 3rd, Rademakers R, Boylan KB, Dickson DW, Petrucelli L (2013) Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS. Neuron 77(4):639–646. doi: 10.1016/j.neuron.2013.02.004

4. Atkin JD, Farg MA, Walker AK, McLean C, Tomas D, Horne MK (2008) Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis. Neurobiol Dis 30(3):400–407. doi: 10.1016/j.nbd.2008.02.009

5. Belzil VV, Bauer PO, Prudencio M, Gendron TF, Stetler CT, Yan IK, Pregent L, Daughrity L, Baker MC, Rademakers R, Boylan K, Patel TC, Dickson DW, Petrucelli L (2013) Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood. Acta Neuropathol 126(6):895–905. doi: 10.1007/s00401-013-1199-1

Cited by 287 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in a AAV-C9ORF72 (G₄C₂)₆₆mouse model;2024-08-27

2. Stress granule formation helps to mitigate neurodegeneration;Nucleic Acids Research;2024-08-06

3. Aberrant protein aggregation in amyotrophic lateral sclerosis;Journal of Neurology;2024-06-13

4. Selenium Nanoparticles as Neuroprotective Agents: Insights into Molecular Mechanisms for Parkinson’s Disease Treatment;Molecular Neurobiology;2024-06-05

5. DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD;Experimental Neurology;2024-06