Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology-Reference-Cited by-同舟云学术

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Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology

Published:2018-12-03 Issue:1 Volume:137 Page:27-46
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

Nana Alissa L.,Sidhu Manu,Gaus Stephanie E.,Hwang Ji-Hye L.,Li Libo,Park Youngsoon,Kim Eun-Joo,Pasquini Lorenzo,Allen Isabel E.,Rankin Katherine P.,Toller Gianina,Kramer Joel H.,Geschwind Daniel H.,Coppola Giovanni,Huang Eric J.,Grinberg Lea T.,Miller Bruce L.,Seeley William W.

Funder

National Institute on Aging

John Douglas French Alzheimer's Foundation

Reserve Talents of Universities Overseas Research Program of Heilongjiang in China

Bluefield Project to Cure FTD

Tau Consortium

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Link

http://link.springer.com/article/10.1007/s00401-018-1942-8/fulltext.html

Reference88 articles.

1. Alfieri JA, Pino NS, Igaz LM (2014) Reversible behavioral phenotypes in a conditional mouse model of TDP-43 proteinopathies. J Neurosci 34:15244–15259. https://doi.org/10.1523/jneurosci.1918-14.2014

2. Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H et al (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 351:602–611. https://doi.org/10.1016/j.bbrc.2006.10.093

3. Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D et al (2013) ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proc Natl Acad Sci USA 110:E736–E745. https://doi.org/10.1073/pnas.1222809110

4. Ash PE, Bieniek KF, Gendron TF, Caulfield T, Lin WL, Dejesus-Hernandez M et al (2013) Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS. Neuron 77:639–646. https://doi.org/10.1016/j.neuron.2013.02.004

5. Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S (2010) Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. J Neurosci 30:639–649. https://doi.org/10.1523/jneurosci.4988-09.2010

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