Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes-Reference-Cited by-同舟云学术

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Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes

Published:2015-11-17 Issue:3 Volume:131 Page:379-391
ISSN:0001-6322
Container-title:Acta Neuropathologica
language:en
Short-container-title:Acta Neuropathol

Author:

Bliederhaeuser Corinna,Grozdanov Veselin,Speidel Anna,Zondler Lisa,Ruf Wolfgang P.,Bayer Hanna,Kiechle Martin,Feiler Marisa S.,Freischmidt Axel,Brenner David,Witting Anke,Hengerer Bastian,Fändrich Marcus,Ludolph Albert C.,Weishaupt Jochen H.,Gillardon Frank,Danzer Karin M.

Funder

Baustein Program Medical Faculty Ulm University

Virtual Helmholtz Institute “RNA dysmetabolims in FTD and ALS” of the Deutsches Zentrum für Neurodegenerative Erkrankungen

Charcot Foundation

Juniorprofessorship Programme Baden-Württemberg

Boehringer Ingelheim Ulm University Biocenter

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00401-015-1504-2.pdf

Reference68 articles.

1. Alvarez-Erviti L, Seow Y, Schapira AH, Gardiner C, Sargent IL, Wood MJ et al (2011) Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission. Neurobiol Dis 42:360–367. doi: 10.1016/j.nbd.2011.01.029

2. Bellingham SA, Guo BB, Coleman BM, Hill AF (2012) Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front Physiol 3:124. doi: 10.3389/fphys.2012.00124

3. Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G et al (2014) Identification of a unique TGF-beta-dependent molecular and functional signature in microglia. Nat Neurosci 17:131–143. doi: 10.1038/nn.3599

4. Chen GY, Nunez G (2010) Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol 10:826–837. doi: 10.1038/nri2873

5. Chernyshev VS, Rachamadugu R, Tseng YH, Belnap DM, Jia Y, Branch KJ et al (2015) Size and shape characterization of hydrated and desiccated exosomes. Anal Bioanal Chem 407:3285–3301. doi: 10.1007/s00216-015-8535-3

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