Preclinical pharmacology of the anthrapyrazole analog oxantrazole (NSC-349174, Piroxantrone)

Author:

Frank Sandra K.,Mathiesen Dane A.,Szurszewski Marie,Kuffel Mary J.,Ames Matthew M.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference20 articles.

1. Alberts DS, Peng YM, Leigh S, Davis TP, Woodward DL (1985) Disposition of mitoxantrone in cancer patients. Cancer Res 45:1879

2. Ames MM, Loprinzi CL (1988) Preliminary pharmacologic and toxicologic data from a phase I clinical trial of oxantrazole incorporating a pharmacologically guided dose-escalation scheme. Proc Amer Assoc Cancer Res 29:196

3. Collins JM, Zaharko DS, Dedrick RL, Chabner BA (1986) Potential roles for preclinical pharmacology in phase I clinical trials. Cancer Treat Rep 70:73

4. Ernster L, Sickevitz P, Palade GE (1962) Enzyme-structure relationships in the endoplasmic reticulum of rat liver. J Cell Biol 15:541

5. Frank SK, Mathiesen DA, Whitfield LR, Ames MM (1987) Reversed phase high performance liquid chromatographic assay for the experimental anticancer anthrapyrazole analog oxantrazole (NSC-349174). J Chromatogr Biomed Appl 419: 225

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