An interleukin-1 receptor antagonist protein protects insulin-producing Beta cells against suppressive effects of interleukin-1?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00403185.pdf
Reference9 articles.
1. Bendtzen K, Mandrup-Poulsen T, Nerup J, Dinarello CA, Svenson M, Nielsen JH (1986) Cytotoxicity of human pl 7 interleukin 1 for pancreatic islets of Langerhans. Science 232: 1545?1547
2. Eizirik DL, Welsh M, Strandell E, Welsh N, Sandler S (1990) Interleukin-1? depletes insulin messenger ribonucleic acid and increases the heat shock protein 70 in mouse pancreatic islets without impairing the glucose metabolism. Endocrinology 127: 2290?2297
3. Sandler S, Bendtzen K, Eizirik DL, Sjöholm Å, Welsh N (1989) Decreased cell replication and polyamine content in insulin-producing cells after exposure to human interleukin 1?. Immunol Lett 22: 267?272
4. Hammonds P, Beggs M, Beresford G, Espinal J, Clarke J, Mertz RJ (1990) Insulin-secreting ?-cells possess specific receptors for interleukin-1?. FEBS Lett 261: 97?100
5. Hughes JH, Colca JR, Easom RA, Turk J, McDaniel ML (1990) Interleukin-1 inhibits insulin secretion from isolated rat pancreatic islets by a process that requires gene transcription and mRNA translation. J Clin Invest 86: 856?863
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