Selective Covalent Inhibition of “Allosteric Cys121” Distort the Binding of PTP1B Enzyme: A Novel Therapeutic Approach for Cancer Treatment
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Biochemistry,General Medicine,Biophysics
Link
http://link.springer.com/content/pdf/10.1007/s12013-019-00882-5.pdf
Reference21 articles.
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2. Shinde, R. N., Siva Kumar, G., Eqbal, S., & Elizabeth Sobhia, M. (2018). Screening and identification of potential PTP1B allosteric inhibitors using in silico and in vitro approaches. PLoS ONE. https://doi.org/10.1371/journal.pone.0199020 .
3. Viswanatharaju Ruddraraju, K., & Zhang, Z.-Y. (2017). Covalent inhibition of protein tyrosine phosphatases. Molecular BioSystems, 13(7), 1257–1279. https://doi.org/10.1039/c7mb00151g .
4. Feldhammer, M., Uetani, N., Miranda-Saavedra, D., & Tremblay, M. L. (2013). PTP1B: a simple enzyme for a complex world. Critical Reviews in Biochemistry and Molecular Biology, 48(5), 430–445. https://doi.org/10.3109/10409238.2013.819830 .
5. Hon, J., Hwang, M. S., Charnetzki, M. A., Rashed, I. J., Brady, P. B., Quillin, S., & Makinen, M. W. (2017). Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates. Journal of Biological Inorganic Chemistry. https://doi.org/10.1007/s00775-017-1500-1 .
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