Perspectives on the development and future of oocyte IVM in clinical practice

Author:

De Vos MichelORCID,Grynberg Michaël,Ho Tuong M.ORCID,Yuan YeORCID,Albertini David F.ORCID,Gilchrist Robert B.ORCID

Abstract

AbstractOocyte in vitro maturation (IVM) is an assisted reproductive technology designed to obtain mature oocytes following culture of immature cumulus–oocyte complexes collected from antral follicles. Although IVM has been practiced for decades and is no longer considered experimental, the uptake of IVM in clinical practice is currently limited. The purpose of this review is to ensure reproductive medicine professionals understand the appropriate use of IVM drawn from the best available evidence supporting its clinical potential and safety in selected patient groups. This group of scientists and fertility specialists, with expertise in IVM in the ART laboratory and/or clinic, explore here the development of IVM towards acquisition of a non-experimental status and, in addition, critically appraise the current and future role of IVM in human ART.

Funder

National Health and Medical Research Council

City Fertility Global

Open Philanthropy

fonds national de la recherche scientifique de belgique

vietnam national foundation for science and technology development

colorado center for reproductive medicine

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Developmental Biology,Obstetrics and Gynaecology,Genetics,Reproductive Medicine,General Medicine

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