Lipopolysaccharide induces oxidative stress and inhibits osteogenic differentiation in periodontal ligament stem cells through downregulating Nrf2

Author:

Chen Yue,Gulinuer Awuti,Zhao Jin

Funder

First Affiliated Hospital of Xinjiang Medical University

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,General Pharmacology, Toxicology and Pharmaceutics,Toxicology,Pathology and Forensic Medicine

Reference31 articles.

1. Bao L et al (2019) Dysfunction of MiR-148a-NRP1 functional axis suppresses osteogenic differentiation of periodontal ligament stem cells under inflammatory microenvironment. Cell Reprogram 21(6):314–322

2. Chen Y et al (2020) Carnosol attenuates RANKL-induced osteoclastogenesis in vitro and LPS-induced bone loss. Int Immunopharmacol 89:106978

3. Dong Z, Yuan Y (2018) Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: ιnhibition by ST1926. Int J Mol Med 41(6):3405–3421

4. Duan et al (2018) Study of platelet-rich fibrin combined with rat periodontal ligament stem cells in periodontal tissue regeneration. J Cell Mol Med 22(2):1047–1055

5. Duan Y, An W, Wu Y, Wang J (2020) Tetramethylpyrazine reduces inflammation levels and the apoptosis of LPS-stimulated human periodontal ligament cells via the downregulation of miR-302b. Int J Mol Med 45(6):1918–1926

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