OSI-027 alleviates rapamycin insensitivity by modulation of mTORC2/AKT/TGF-β1 and mTORC1/4E-BP1 signaling in hyperoxia-induced lung injury infant rats-Reference-Cited by-同舟云学术

OSI-027 alleviates rapamycin insensitivity by modulation of mTORC2/AKT/TGF-β1 and mTORC1/4E-BP1 signaling in hyperoxia-induced lung injury infant rats

Published:2021-04-01 Issue: Volume: Page:
ISSN:1738-642X
Container-title:Molecular & Cellular Toxicology
language:en
Short-container-title:Mol. Cell. Toxicol.

Author:

Long Li,Liang Mulin,Liu Yanling,Wang Pan,Dang Hongxing

Funder

Natural Science Foundation of Chongqing

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health,General Pharmacology, Toxicology and Pharmaceutics,Toxicology,Pathology and Forensic Medicine

Link

http://link.springer.com/content/pdf/10.1007/s13273-021-00131-y.pdf

Reference32 articles.

1. Andreollo NA, de Santos EF, Araújo MR, Lopes LR (2012) Rat’s age versus human’s age: what is the relationship? Arq Bras Cir Dig 25:49–51

2. Bahrami A, Khazaei M, Hasanzadeh M, ShahidSales S, Joudi Mashhad M, Farazestanian M et al (2018) Therapeutic potential of targeting PI3K/AKT pathway in treatment of colorectal cancer: rational and progress. J Cell Biochem 119:2460–2469

3. Bonniaud P, Margetts PJ, Ask K, Flanders K, Gauldie J, Kolb M (2005) TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis. J Immunol 175:5390–5395

4. Dang H-X, Li J, Liu C, Fu Y, Zhou F, Tang L et al (2017) CGRP attenuates hyperoxia-induced oxidative stress-related injury to alveolar epithelial type II cells via the activation of the Sonic hedgehog pathway. Int J Mol Med 40:209–216

5. Dejust S, Morland D, Bruna-Muraille C, Eymard J-C, Yazbek G, Savoye A-M et al (2018) Everolimus-induced pulmonary toxicity: findings on 18F-FDG PET/CT imaging. Medicine (Baltimore) 97:e12518