Nonlinear renal elimination kinetics of methotrexate due to saturation of renal tubular reabsorption
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/BF00546719.pdf
Reference11 articles.
1. Goldie JH, Price LA, Harrap KR (1972) Methotrexate toxicity: Correlation with duration of administration, plasma levels, dose and excretion pattern. Eur J Cancer 8: 409?414
2. Goresky CA, Watanabe H, Johns DC (1963) The renal excretion of folic acid. J Clin Invest 42: 1841?1849
3. Hendel J, Sarek LJ, Hvidberg EF (1976) Rapid radioimmunoassay for methotrexate in biological fluids. Clin Chem 22: 813?816
4. Huffman DH, Wan SK, Azarnoff DL, Hoogstraten B (1973) Pharmacokinetics of methotrexate. Clin Pharmacol Ther 14: 572?579
5. Lawrence JR, Steele WH, Stuart JFB, McNeill CA, McVie, Whiting B (1980) Dose dependent methotrexate elimination following bolus intravenous injection. Eur J Clin Pharmacol 17: 371?374
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