Inverse Salt Sensitivity of Blood Pressure: Mechanisms and Potential Relevance for Prevention of Cardiovascular Disease

Author:

Felder Robin A.,Gildea John J.,Xu Peng,Yue Wei,Armando Ines,Carey Robert M.,Jose Pedro A.

Funder

National Heart, Lung, and Blood Institute

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Springer Science and Business Media LLC

Subject

Internal Medicine

Reference136 articles.

1. Whelton PK, Carey RM, Aronow WS, Casey DE, Collins KJ, Dennison Himmelfarb C, DePalma SM, Gidding S, Jamerson KA, Jones DW, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2018;138:e484–594.

2. •• He FJ, Tan M, Ma Y, MacGregor GA. Salt reduction to prevent hypertension and cardiovascular disease: JACC state-of-the-art review. J Am Coll Cardiol. 2020;75:632–47. This comprehensive review highlights the important role of elevated dietary salt in cardiovascular disease with or without elevated blood pressure.

3. •• Cappuccio FP, Beer M, Strazzullo P, Network ESA. Population dietary salt reduction and the risk of cardiovascular disease. A scientific statement from the European Salt Action Network. Nutr Metab Cardiovasc Dis. 2018;29:107–114. This paper discusses the fact that a low salt diet can lead to increased morbidity and mortality.

4. Elfassy T, Chamany S, Bartley K, Yi SS, Angell SY. Lower 24-h urinary sodium excretion is associated with hypertension control: the 2010 Heart Follow-Up Study. J Hum Hypertens. 2020;34:624–32.

5. Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, Park MJ, Sobota RS, Underwood PC, Williams J, et al. Salt sensitivity of blood pressure is associated with polymorphisms in the sodium-bicarbonate cotransporter. Hypertension. 2012;60:1359–66.

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