Cytostatic Drugs, Neuregulin Activation of ErbB Receptors, and Angiogenesis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11906-010-0148-9.pdf
Reference50 articles.
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3. Meyer D, Yamaai T, Garratt A, et al.: Isoform-specific expression and function of neuregulin. Development 1997, 124:3575–3586.
4. Liu X, Gu X, Li Z, et al.: Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol 2006, 48:1438–1447.
5. • Gao R, Zhang J, Cheng L, et al.: A phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol 2010, 55:1907–1914. This is the first published clinical trial of neuregulin in patients with heart failure.
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