Insulin signaling in heart muscle: Lessons from genetically engineered mouse models
Author:
Publisher
Springer Science and Business Media LLC
Subject
Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11906-004-0034-4.pdf
Reference55 articles.
1. Belke DD, Betuing S, Tuttle MJ, et al.: Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. J Clin Invest 2002, 109:629–639. In this article, the initial description of the phenotype of CIRKO mice was presented, namely: reduced cardiac size, persistent fetal myosin isoform expression, and reduced rates of glucose and fatty acid metabolism.
2. Campbell FM, Kozak R, Wagner A, et al.: A role for peroxisome proliferator-activated receptor alpha (PPARalpha) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated with higher concentrations of malonyl-CoA and reduced expression of malonyl-CoA decarboxylase. J Biol Chem 2002, 277:4098–4103.
3. Taegtmeyer H, McNulty P, Young ME: Adaptation and maladaptation of the heart in diabetes: Part I: general concepts. Circulation 2002, 105:1727–1733.
4. Finck BN, Lehman JJ, Leone TC, et al.: The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest 2002, 109:121–130. The cardiac phenotype of transgenic overexpression of PPARá in the heart is presented.
5. Abel ED: Glucose transport in the heart. Front Biosci 2004, 9:201–215.
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