Role of Collecting Duct Renin in the Pathogenesis of Hypertension-Reference-Cited by-同舟云学术

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Role of Collecting Duct Renin in the Pathogenesis of Hypertension

Published:2017-07-10 Issue:8 Volume:19 Page:
ISSN:1522-6417
Container-title:Current Hypertension Reports
language:en
Short-container-title:Curr Hypertens Rep

Author:

Gonzalez Alexis A.,Lara Lucienne S.,Prieto Minolfa C.

Funder

The National Institutes of Health (US)

LACaTS Center

FONDECYT-Chile

Science National Council for Scientific and Technological Development (CNPq)‐Brazil

Science Without Borders grant from CNPq‐Brazil

Publisher

Springer Science and Business Media LLC

Subject

Internal Medicine

Link

http://link.springer.com/article/10.1007/s11906-017-0763-9/fulltext.html

Reference49 articles.

1. Hackenthal E, Paul M, Ganten D, Taugner R. Morphology, physiology, and molecular-biology of renin secretion. Physiol Rev. 1990;70(4):1067–116.

2. Rohrwasser A, Morgan T, Dillon HF, Zhao L, Callaway CW, Hillas E, et al. Elements of a paracrine tubular renin-angiotensin system along the entire nephron. Hypertension. 1999;34(6):1265–74.

3. •• Gonzalez AA, Liu L, Lara LS, Bourgeois CRT, Ibaceta-Gonzalez C, Salinas-Parra N, et al. PKC-alpha-dependent augmentation of cAMP and CREB phosphorylation mediates the angiotensin II stimulation of renin in the collecting duct. Am J Physiol-Renal. 2015;309(10):E880–8. This study demonstrated that Ang II feedforwards collecting duct renin via PKCα, which allows the augmentation of cAMP production and the activation of PKA/CREB pathway via AC6.

4. Beazely MA, Watts VJ. G alpha(q)-coupled receptor signaling enhances adenylate cyclase type 6 activation. Biochem Pharmacol. 2005;70(1):113–20.

5. Rozengurt E, Murray M, Zachary I, Collins M. Protein-kinase-C activation enhances camp accumulation in Swiss 3t3 cells—inhibition by pertussis toxin. P Natl Acad Sci USA. 1987;84(8):2282–6.

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