Role of Thioredoxin in Age-Related Hypertension

Author:

Das Kumuda C.,Kundumani-Sridharan Venkatesh,Subramani Jaganathan

Publisher

Springer Science and Business Media LLC

Subject

Internal Medicine

Reference110 articles.

1. Fujimoto H, Kobayashi H, Ohno M. Age-induced reduction in mitochondrial manganese superoxide dismutase activity and tolerance of macrophages against apoptosis induced by oxidized low density lipoprotein. Circ J. 2010;74(2):353–60. https://doi.org/10.1253/circj.CJ-09-0491 .

2. Pansarasa O, Bertorelli L, Vecchiet J, Felzani G, Marzatico F. Age-dependent changes of antioxidant activities and markers of free radical damage in human skeletal muscle. Free Radic Biol Med. 1999;27(5–6):617–22. https://doi.org/10.1016/S0891-5849(99)00108-2 .

3. • Pawluk H, Pawluk R, Robaczewska J, Kedziora-Kornatowska K, Kedziora J. Biomarkers of antioxidant status and lipid peroxidation in elderly patients with hypertension. Redox Rep. 2017;22:542–546. https://doi.org/10.1080/13510002.2017.1372072 . This review shows high levels of oxidative markers in hypertensive patients linking aged-related oxidation to hypertension in humans.

4. • de Almeida A, Ribeiro TP, de Medeiros IA. Aging: molecular pathways and implications on the cardiovascular system. Oxidative Med Cell Longev. 2017;2017:7941563. https://doi.org/10.1155/2017/7941563 . This article reviewed age-related oxidative pathways that contibutes to cardiovascular diseases.

5. • Paneni F, Diaz Canestro C, Libby P, Luscher TF, Camici GG. The Aging Cardiovascular System: Understanding It at the Cellular and Clinical Levels. J Am Coll Cardiol. 2017;69(15):1952–67. https://doi.org/10.1016/j.jacc.2017.01.064 . This review describes clinically identifiable factors associated with aging cardiovascular system and possible molecular mechanisms related to age related changes in heart and vasculature.

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