How high should an ACE inhibitor or angiotensin receptor blocker be dosed in patients with diabetic nephropathy?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Internal Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11906-003-0088-8.pdf
Reference63 articles.
1. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Kidney Disease Outcome Quality Initiative. Am J Kidney Dis 2002, 39:S1–S246.
2. Arauz-Pacheco C, Parrott MA, Raskin P: Treatment of hypertension in adults with diabetes. Diabetes Care 2003, 26:S80-S82.
3. Molitch ME, DeFronzo RA, Franz MJ, et al.: Diabetic nephropathy. Diabetes Care 2003, 26:S94-S98.
4. Lewis EJ, Hunsicker LG, Clarke WR, et al.: Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001, 345:851–886. The first of the two large studies that accounted for an ARB recommendation in type 2 diabetes. In this study the superiority of irbesartan was shown compared with amlodipine.
5. Brenner BM, Cooper ME, de Zeeuw D, et al.: Effects of losartan on renal and cardiovascular outcomes in patients with type diabetes and nephropathy. N Engl J Med 2001, 345:861–869. This study clearly disclosed the significant effect of the ARB (losartan) on preventing the progression to hard endpoints.
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