Plasticity of Renin Cells in the Kidney Vasculature

Author:

Gomez R. Ariel,Lopez Maria Luisa S. Sequeira

Publisher

Springer Science and Business Media LLC

Subject

Internal Medicine

Reference10 articles.

1. Keeton TK, Campbell WB. The pharmacological alteration of renin release. Pharmacol Rev. 1980;32:81–227.

2. Gomez RA, Sequeira Lopez MLS. Novel functions of renin precursors in homeostasis and disease. Physiology. 2015;31:25–33.

3. Cantin M, Araujo-Nascimento M, Benchimol S, Desormeaux Y. Metaplasia of smooth muscle cells into juxtaglomerular cells in the juxtaglomerular apparatus, arteries, and arterioles of the ischemic (endocrine) kidney. Am J Pathol. 1977;87:581–602.

4. ••Gomez RA, Chevalier RL, Everett AD, Elwood JP, Peach MJ, Lynch KR, et al. Recruitment of renin gene expressing cells in the adult rat kidney. Am J Physiol. 1990;259:F660F665. This study demonstrated that “recruitment” was due to an increase in the number of smooth muscle cells expressing the renin gene. It was further proposed that native/resident vascular smooth muscle cells were transformed an induced to express renin in order to control homeostasis.

5. Everett AD, Carey RM, Peach MJ, Gomez RA. Renin release and gene expression in intact rat kidney microvessels and single cells. J Clin Invest. 1990;86:169–75.

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