CFD assessment of the effect of convective mass transport on the intracellular clearance of intracellular triglycerides in macrosteatotic hepatocytes

Author:

Yarmush Gabriel,Santos Lucas,Yarmush Joshua,Koundinyan Srivathsan,Saleem Mubasher,Nativ Nir I.,Yarmush Martin L.,Berthiaume Francois,Maguire Timothy J.ORCID,Guaghan Chris

Publisher

Springer Science and Business Media LLC

Subject

Mechanical Engineering,Modeling and Simulation,Biotechnology

Reference29 articles.

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2. Berthiaume F, Barbe L, Mokuno Y, MacDonald AD, Jindal R, Yarmush ML (2009) Steatosis reversibly increases hepatocyte sensitivity to hypoxia-reoxygenation injury. J Surg Res 152:54–60

3. Chang TK, Waxman DJ (2006) Enzymatic analysis of cdna-expressed human cyp1a1, cyp1a2, and cyp1b1 with 7-ethoxyresorufin as substrate. Methods Mol Biol 320:85–90

4. Dashti N, Feng Q, Franklin FA (2000) Long-term effects of cis and trans monounsaturated (18:1) and saturated (16:0) fatty acids on the synthesis and secretion of apolipoprotein a-i- and apolipoprotein b-containing lipoproteins in HepG2 cells. J Lipid Res 41:1980–1990

5. Farrell GC, Teoh NC, McCuskey RS (2008) Hepatic microcirculation in fatty liver disease. Anat Rec 291:684–692

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