Tributyrin emulsion as a potent inhibitor of serum- or heregulin-stimulated proliferation of colon cancer cells

Author:

Lim Soo-Jeong,Choi Moon-Kyung

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science

Reference14 articles.

1. Augenlicht LH, Mariadason JM, Wilson A, Arango D, Yang W, Heerdt BG, Velcich A (2002) Short chain fatty acids and colon cancer. J Nutr 132:3804S–3808S

2. Carraway KL 3rd, Soltoff SP, Diamonti AJ, Cantley LC (1995) Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3. J Biol Chem 270:7111–7116

3. Chen ZX, Breitman TR (1994) Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy. Cancer Res 54:3494–3499

4. Fung KY, Brierley GV, Henderson S, Hoffmann P, McColl SR, Lockett T, Head R, Cosgrove L (2011) Butyrate-induced apoptosis in HCT116 colorectal cancer cells includes induction of a cell stress response. J Proteome Res 10:1860–1869

5. Heerdt BG, Houston MA, Anthony GM, Augenlicht LH (1999) Initiation of growth arrest and apoptosis of MCF-7 mammary carcinoma cells by tributyrin, a triglyceride analogue of the short-chain fatty acid butyrate, is associated with mitochondrial activity. Cancer Res 59:1584–1591

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