TLR2-Dependent Reversible Oxidation of Connexin 43 at Cys260 Modifies Electrical Coupling After Experimental Myocardial Ischemia/Reperfusion

Author:

Raimann Florian JürgenORCID,Dröse Stefan,Bonke Erik,Schneider Lea,Tybl Elisabeth,Wittig Ilka,Heidler Juliana,Heide Heinrich,Josipovic Ivana,Leisegang Matthias,Brandes Ralf Peter,Roeper Jochen,Zacharowski Kai,Mersmann Jan

Funder

Deutsche Forschungsgemeinschaft

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Cardiology and Cardiovascular Medicine,Pharmaceutical Science,Genetics,Molecular Medicine

Reference30 articles.

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2. Mersmann, J., Iskandar, F., Latsch, K., Habeck, K., Sprunck, V., Zimmermann, R., Schumann, R. R., Zacharowski, K., & Koch, A. (2013). Attenuation of myocardial injury by HMGB1 blockade during ischemia/reperfusion is toll-like receptor 2-dependent. Mediators of Inflammation, 2013, 174168.

3. Sakata, Y., Dong, J.-W., Vallejo, J. G., Huang, C.-H., Baker, J. S., Tracey, K. J., Tacheuchi, O., Akira, S., & Mann, D. L. (2007). Toll-like receptor 2 modulates left ventricular function following ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology, 292(1), H503–H509.

4. Zhang, J.-X., Wu, H.-S., Wang, H., Zhang, J.-H., Wang, Y., & Zheng, Q.-C. (2005). Protection against hepatic ischemia/reperfusion injury via downregulation of toll-like receptor 2 expression by inhibition of Kupffer cell function. World Journal of Gastroenterology, 11(28), 4423–4426.

5. Mersmann, J., Koch, A., Tran, N., Zimmermann, R., Granja, T. F., Larmann, J., Herzog, C., Theilmeier, G., Bornstein, S. R., Kirschning, C. J., & Zacharowski, K. (2010). Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion. Critical Care Medicine, 38(10), 1927–1932.

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