T2238C Atrial Natriuretic Peptide Gene Variant and the Response to Antiplatelet Therapy in Stable Ischemic Heart Disease Patients
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Published:2017-12-05
Issue:1
Volume:11
Page:36-41
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ISSN:1937-5387
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Container-title:Journal of Cardiovascular Translational Research
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language:en
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Short-container-title:J. of Cardiovasc. Trans. Res.
Author:
Strisciuglio Teresa,Barbato Emanuele,De Biase Chiara,Di Gioia Giuseppe,Cotugno Maria,Stanzione Rosita,Trimarco Bruno,Sciarretta Sebastiano,Volpe Massimo,Wijns Wiliam,Delrue Leen,Rubattu Speranza
Funder
Italian Ministry of Health Cardiopath PhD program
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Cardiology and Cardiovascular Medicine,Pharmaceutical Science,Genetics,Molecular Medicine
Reference23 articles.
1. Rubattu, S., Sciarretta, S., & Volpe, M. (2014). Atrial natriuretic peptide gene variants and circulating levels: implications in cardiovascular diseases. Clinical Science, 127, 1–13. 2. Scarpino, S., Marchitti, S., Stanzione, R., Evangelista, A., Di Castro, S., Savoia, C., Quarta, G., Sciarretta, S., Ruco, L., Volpe, M., & Rubattu, S. (2009). ROS-mediated differential effects of the human atrial natriuretic peptide T2238C genetic variant on endothelial cells in vitro. Journal of Hypertension, 27, 1804–1813. 3. Sciarretta, S., Marchitti, S., Bianchi, F., Moyes, A., Barbato, E., Di Castro, S., Stanzione, R., Cotugno, M., Castello, L., Calvieri, C., Eberini, I., Sadoshima, J., Hobbs, A. J., Volpe, M., & Rubattu, S. (2013). The C2238 atrial natriuretic peptide molecular variant is associated with endothelial damage and dysfunction through natriuretic peptide receptor C signaling. Circulation Research, 112, 1355–1364. 4. Rubattu, S., Marchitti, S., Bianchi, F., Di Castro, S., Stanzione, R., Cotugno, M., Bozzao, C., Sciarretta, S., & Volpe, M. (2014). The C2238/αANP variant is a negative modulator of both viability and function of coronary artery smooth muscle cells. PLoS One, 9, e113108. 5. Carnevale, R., Pignatelli, P., Frati, G., Nocella, C., Stanzione, R., Pastori, D., Marchitti, S., Valenti, V., Santulli, M., Barbato, E., Strisciuglio, T., Schirone, L., Vecchione, C., Violi, F., Volpe, M., Rubattu, S., & Sciarretta, S. (2017). C2238 ANP gene variant promotes increased platelet aggregation through the activation of Nox2 and the reduction of cAMP. Scientific Reports, 7, 3797.
Cited by
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