Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
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Published:2021-05-11
Issue:6
Volume:14
Page:1043-1050
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ISSN:1937-5387
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Container-title:Journal of Cardiovascular Translational Research
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language:en
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Short-container-title:J. of Cardiovasc. Trans. Res.
Author:
Naar JanORCID, Skalský Ivo, Krűger Andreas, Málek Filip, Van Bladel Kevin, Annest Lon S., Moučka Petr, Mráz Tomáš, Reddy Vivek Y., Neužil Petr
Abstract
AbstractThe evidence supporting surgical aneurysmectomy in ischemic heart failure is inconsistent. The aim of the study was to describe long-term effect of minimally invasive hybrid transcatheter and minithoracotomy left ventricular (LV) reconstruction in patients with ischemic cardiomyopathy. Twenty-three subjects with transmural anterior wall scarring, LV ejection fraction 15–45%, and New York Heart Association class ≥ II were intervened using Revivent TC anchoring system. LV end-systolic volume index was reduced from 73.2 ± 27 ml at baseline to 51.5 ± 22 ml after 6 months (p < 0.001), 49.9 ± 20 ml after 2 years (p < 0.001), and 56.1 ± 16 ml after 5 years (p = 0.047). NYHA class improved significantly at 5 years compared to baseline. Six-min walk test distance increased at 2 years compared to the 6-month visit. Hybrid LV reconstruction using the anchoring system provides significant and durable LV volume reduction during 5-year follow-up in preselected patients with ischemic heart failure.
Graphical abstract
Funder
Ministerstvo Zdravotnictví Ceské Republiky
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Cardiology and Cardiovascular Medicine,Pharmaceutical Science,Genetics,Molecular Medicine
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