Human autopsy-tissue distribution of menogaril and its metabolites

Author:

Stewart David J.,Grewaal Darshan,Green Robert M.,Goel Rakesh,Mikhael Nadia,Montpetit Vital A. J.,Redmond Deidre,Earhart Robert

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference27 articles.

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2. Cummings J, McArdle CS (1986) Studies on the in vivo disposition of Adriamycin in human tumours which exhibit different responses to the drug. Br J Cancer 53: 835?838

3. Dodion P, Egorin MJ, Engisch KL, Bachur NR (1985) Metabolism and disposition of menogaril (NSC 269148) in the rabbit. Cancer Res 45: 5352?5357

4. Egorin MJ, Van Echo DA, Whitacre MY, Forrest A, Sigman LM, Engisch KL, Aisner J (1986) Human pharmacokinetics, excretion, and metabolism of the anthracycline antibiotic menogaril (7-OMEN, NSC 269148) and their correlation with clinical toxicities. Cancer Res 46: 1513?1520

5. Eisenhauer EA, Pritchard KI, Perrault DJ, Verma S, Pater JL (1990) Activity of intravenous menogaril in patients with previously untreated metastatic breast cancer. A National Cancer Institute of Canada Clinical Trials Group study. Invest New Drugs 8: 283?287

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