Abstract
Abstract
Purpose
Emergency laparotomy is associated with high morbidity for the surgical patient. Understanding patients’ health-related quality of life after their surgery is important to enhance the informed consent process, and to enable the evaluation and improvement of surgical care. This review aims to summarise the use of health-related quality of life tools in clinical trials involving patients undergoing emergency laparotomy.
Methods
A systematic review was undertaken of the scientific literature published in the MEDLINE® and PubMed databases between January 2011 and July 2021. A narrative synthesis approach was chosen to synthesise the diverse range of studies in a structured manner. All included papers were evaluated using the Cochrane Collaboration’s tool for assessing risk of bias.
Results
Eleven studies were selected for inclusion. Most of the studies had a low risk of bias. Two of the studies used health-related quality of life as the primary outcome measure. A variety of health-related quality of life measurement tools were used; the EQ-5D tool was the most popular questionnaire. Protocol adherence was dependent on the length of time which had elapsed after emergency surgery.
Conclusion
There are many perceived challenges to collecting health-related quality of life data in the emergency surgery setting. Many of these can be offset with progressive trial designs. There is a need for further research in the systematic development of patient-reported outcomes for use in emergency surgery.
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health
Reference24 articles.
1. Holt, P. J. E., Sinha, S., Ozdemir, B. A., Karthikesalingam, A., Poloniecki, J. D., & Thompson, M. M. (2014). Variations and inter-relationship in outcome from emergency admissions in England: A retrospective analysis of Hospital Episode Statistics from 2005–2010. BMC Health Services Research, 14, 270.
2. NHS Digital. (2017). Hospital admitted patient care activity, 2016–17. Hosp Admit Patient Care Act.
3. Stoneham, M., Murray, D., & Foss, N. (2014). Emergency surgery: The big three-abdominal aortic aneurysm, laparotomy and hip fracture. Anaesthesia, 69, 70–80.
4. Stevens, D. J., Blencowe, N. S., McElnay, P. J., Macefield, R. C., Savović, J., Avery, K. N., & Blazeby, J. M. (2016). A systematic review of patient-reported outcomes in randomized controlled trials of unplanned general surgery. World Journal of Surgery, 40, 267–76. https://doi.org/10.1007/s00268-015-3292-1
5. NICE. Guide to the methods of technology appraisal 2013. Guid Guidel. 2013. https://www.nice.org.uk/process/pmg9/chapter/foreword.