Role of prostaglandin deficiency in pathogenetic mechanism of gastric lesions induced by indomethacin in rats

Author:

Okada Megumu,Niida Hiromichi,Takeuchi Koji,Okabe Susumu

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology,Physiology

Reference22 articles.

1. Djahanguiri B: The production of acute gastric ulceration by indomethacin in the rat. Scand J Gastroenterol 4:265?267, 1969

2. Robert A: Prostaglandins and the gastrointestinal tract.In Physiology of the Gastrointestinal Tract. Edited by LR Johnson, J Cristensen, MI Grossman, ED Jacobson, SG Shultz (eds). Raven Press, New York, 1981, pp 1407?1434

3. Lanza FL: Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal antiinflammatory agents. Am J Med 13:19?24, 1984

4. Whittle BJR: Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat. Gastroenterology 80:94?98, 1981

5. Takeuchi K, Ueki S, Okabe S: Importance of gastric motility in the pathogenesis of indomethacin-induced gastric lesions in rats. Dig Dis Sci 31:1114?1121, 1986

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