1. For a discussion of MEDLARS, see M. Day, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33, 1717 (1974). Indexing is done by specially trained abstractors at the National Library of Medicine. The MEDLARS contents vary over time as additions are made to correct omissions. Our initial search turned up 36 randomized clinical trials. These are listed in (6), appendix 9-1, pp. 145–154. A repeat search, approximately 18 months later, done according to the same search instructions, revealed 13 additional randomized clinical trials as follows: R.B. Noone, P. Randall, S.E. Stool, R. Hamilton, R.A. Winchester, Cleft Palate J. 10, 23 (1973); R. Smith, Trans. Ophthalmol. Soc. Aust. 27, 17 (1968); B. Brehmer and P.O. Madsen, J. Urol. 108, 719 (1972); J.E. Rothermel, J.B. Wessinger, F.E. Stinchfield, Arch. Surg. 106, 135 (1973); R.K. Laros, G.I. Zatuchni, G.J. Andros, Obstet. Gynecol. 41, 397 (1973); W.H. Harris, E.W. Salzman, R.W. DeSanctis, R.D. Coutts, J. Am. Med. Assoc. 220, 1319 (1972); J.W. Roddick, Jr., and R.H. Greenelaw, Am. J. Obstet. Gynecol. 109, 754 (1971); I.L. Rosenberg, N.G. Graham, F.T. DeDombal, J.C. Goligher, Br. J. Surg. 58, 266 (1971); R. Brisman, L.C. Parks, J.A. Haller, Jr., Ann. Surg. 174, 137 (1971); J.M. Lambie, D.C. Barber, D.P. Dhall, N.A. Matheson, Br. Med. J. 2, 144 (1970), D.B. Haverstadt and G.W. Leadbetter, Jr., J. Urol. 100, 297 (1968); J.A. Haller, Jr., et al., Ann Surg. 177, 595 (1973); D.J. Pinto, East Afr. Med. J. 49, 643 (1972).
2. A.B. Miller, W. Fox, R. Tall, Lancet 1969-II, 501 (1969).
3. B. Efon and C. Morris, J. Am. Stat. Assoc. 68, 117 (1973).
4. —, J. R. Stat. Soc. B 35, 379 (1973).
5. —, Sci. Am. 236,(No. 5) 119 (1977).