Molecular crowding accelerates aggregation of α-synuclein by altering its folding pathway
Author:
Funder
Science and Engineering Research Board
Publisher
Springer Science and Business Media LLC
Subject
General Medicine,Biophysics
Link
http://link.springer.com/content/pdf/10.1007/s00249-020-01486-1.pdf
Reference46 articles.
1. Alderson TR, Markley JL (2013) Biophysical characterization of α-synuclein and its controversial structure. Intrinsically Disord Proteins 1:18–39
2. Anand JC, Brown AD (1968) Growth rate patterns of the so-called osmophilic and non-osmophilic yeasts in solutions of polyethylene glycol. J Gen Microbiol 52:205–212
3. Bartels T, Choi JG, Selkoe DJ (2011) alpha-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation. Nature 477:107–110
4. Bodles AM, Guthrie DJ, Greer B, Irvine GB (2001) Identification of the region of non-Abeta component (NAC) of Alzheimer’s disease amyloid responsible for its aggregation and toxicity. J Neurochem 78:384–395
5. Breydo L, Sales AE, Frege T, Howell MC, Zaslavsky BY, Uversky VN (2015) Effects of polymer hydrophobicity on protein structure and aggregation kinetics in crowded milieu. Biochemistry 54:2957–2966
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