The Role of Chondrocyte Morphology and Volume in Controlling Phenotype—Implications for Osteoarthritis, Cartilage Repair, and Cartilage Engineering
Author:
Funder
University of Edinburgh
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://link.springer.com/content/pdf/10.1007/s11926-019-0837-6.pdf
Reference123 articles.
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2. Pitsillides AA, Beier F. Cartilage biology in osteoarthritis – lessons from developmental biology. Nat Rev Rheumatol. 2011;7:654–63. https://doi.org/10.1038/nrrheum.2011.12.9 .
3. Aigner T, Soder S, Gebhard PM, McAlinden A, Haag J. Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis – structure, chaos and senescence. Nature Rheumatol. 2007;3(7):391–9. https://doi.org/10.1038/ncprheum0534 .
4. •• Graceffa V, Vinatier C, Guicheux J, Stoddart M, Alini M, Zeugolis DI. Chasing chimeras – the elusive stable chondrogenic phenotype. Biomaterials 2019:192;199–192;235. https://doi.org/10.1016/j.biomaterials.2018.11.014 . An important review which highlights the importance of a stable chondrocyte phenotype in maintaining hyaline-like matrix.
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