Bone health and systemic lupus erythematosus

Author:

Lee Chin,Ramsey-Goldman Rosalind

Publisher

Springer Science and Business Media LLC

Subject

Rheumatology

Reference32 articles.

1. Yee CS, Crabtree N, Skan J, et al.: Prevalence and predictors of fragility fractures in systemic lupus erythematosus. Ann Rheum Dis 2005, 64:111–113. One of the largest studies to ascertain fracture prevalence and associated predictors in 242 patients with SLE. Reduced BMD and age were signifi-cantly associated with fragility fractures since diagnosis of SLE, whereas corticosteroid exposure was not a significant factor.

2. Redlich K, Ziegler S, Kiener HP, et al.: Bone mineral density and biochemical parameters of bone metabolism in female patients with systemic lupus erythematosus. Ann Rheum Dis 2000, 59:308–310.

3. Kalla AA, Fataar AB, Jessop SJ, Bewerunge L: Loss of trabecular bone mineral density in systemic lupus erythematosus. Arthritis Rheum 1993, 36:1726–1734.

4. Sinigaglia L, Varenna M, Binelli L, et al.: Determinants of bone mass in systemic lupus erythematosus: a cross sectional study on premenopausal women. J Rheumatol 1999, 26:1280–1284. The study assessed determinants of bone mass in 84 premenopausal women with SLE and found 22.6% of patients to have osteoporosis. Patients with osteoporosis had greater disease damage and longer disease duration, but also had higher cumulative corticosteroid intake and longer corticosteroid use.

5. Pineau CA, Urowitz MB, Fortin PJ, et al.: Osteoporosis in systemic lupus erythematosus: factors associated with referral for bone mineral density studies, prevalence of osteoporosis and factors associated with reduced bone density. Lupus 2004, 13:436–441. In 205 women with SLE, increased damage and age were associated with low BMD. However, disease activity and corticosteroid use were not associated with osteoporosis.

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