Microchimerism and scleroderma: An update
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://link.springer.com/content/pdf/10.1007/s11926-003-0044-2.pdf
Reference39 articles.
1. Artlett CM, Smith JB, Jimenez SA: Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis. N Eng J Med 1998, 338:1186–1191. This paper is a seminal publication that demonstrates, for the first time, the presence of fetal microchimeric cells in the active lesions of patients with SSc, and also that microchimeric cells in the peripheral blood are CD3+ T cells.
2. Artlett CM, Cox LA, Ramos RC, et al.: Increased microchimeric CD4+ T lymphocytes in peripheral blood from women with systemic sclerosis. Clin Immunol 2002, 103:303–308. This paper identifies the presence of fetal microchimeric cells in the CD4+ T cell population in peripheral blood. CD4+ T cells are important effector molecules in mediating GVHD. This article adds support to the hypothesis that SSc may be a GVHD mediated disease.
3. Artlett CM, Welsh KI, Black CM, Jimenez SA: Fetal-maternal HLA compatibility confers susceptibility to systemic sclerosis. Immunogenetics 1997, 47:17–22. This article is the first report of HLA class II compatibility between SSc patients and offspring and their mothers
4. Nelson JL, Furst DE, Maloney S, et al.: Microchimerism and HLA-compatible relationships of pregnancy in scleroderma. Lancet 1998, 351:559–562. This publication confirms the Artlett et al. [3] study by demonstrating HLA compatibility in SSc families; it also demonstrates microchimeric cells in the peripheral blood of women with SSc.
5. Artlett CM: Microchimerism in health and disease. Curr Molec Med 2002, 2:525–535.
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2. Microchimérisme fœtal : soi et non soi, finalement qui sommes-nous ?;Journal de Gynécologie Obstétrique et Biologie de la Reproduction;2011-09
3. Microchimérisme fœtal : un bien ou un mal pour le fœtus et sa mère ?;Gynécologie Obstétrique & Fertilité;2011-04
4. Systemische Sklerose - eine systematische Übersicht;Vasa;2011-01-01
5. Scleroderma;Challenging Cases in Allergic and Immunologic Diseases of the Skin;2010
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