Catastrophic antiphospholipid syndrome

Author:

Asherson Ronald A.,Cervera Ricard

Publisher

Springer Science and Business Media LLC

Subject

Rheumatology

Reference17 articles.

1. Asherson RA: The catastrophic antiphospholipid antibody syndrome. J Rheumatol 1992, 19:508–512. Although from 1992, this was the first paper defining and documenting this condition in 10 reported cases, and the definition presented more than 10 years ago still hold true today. Multiorgan failure is the hallmark of this condition with small-vessel occlusive disease dominating the clinical picture.

2. Asherson RA, Cervera R, Piette JC, et al.: Catastrophic antibody syndrome: clinical and laboratory features of 50 patients. Medicine (Baltimore) 1998, 77:195–207.

3. Asherson RA, Cervera R, Piette JC, et al.: Catastrophic antiphospholipid syndrome: clues to the pathogenesis from a series of 80 patients. Medicine (Baltimore) 2001, 80:355–376. These two articles summarize the clinical and laboratory characteristics of a total of 130 patients with catastrophic APS. Infections and other precipitating factors were recorded as “triggers” for the development of the condition.

4. Cervera R, Piette JC, Font J, et al.: Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum 2002, 46:1019–1027.

5. Asherson RA, Shoenfeld Y: The role of infection in the pathogenesis of catastrophic antiphospholipid syndrome: molecular mimicry? J Rheumatol 2000, 27:12–14.

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