The Representation of Gender and Race/Ethnic Groups in Randomized Clinical Trials of Individuals with Systemic Lupus Erythematosus

Author:

Falasinnu Titilola,Chaichian Yashaar,Bass Michelle B.,Simard Julia F.

Publisher

Springer Science and Business Media LLC

Subject

Rheumatology

Reference33 articles.

1. Mak A, Tay SH. Environmental factors, toxicants and systemic lupus erythematosus. Int J Mol Sci. [Internet]. Multidisciplinary Digital Publishing Institute (MDPI); 2014 [cited 2017 Nov 21];15:16043–56. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25216337 .

2. Weckerle CE, Niewold TB. The unexplained female predominance of systemic lupus erythematosus: clues from genetic and cytokine studies. Clin Rev Allergy Immunol. [Internet]. 2011 [cited 2017 Mar 27];40:42–9. Available from: http://link.springer.com/10.1007/s12016-009-8192-4

3. Murphy G, Isenberg D. Effect of gender on clinical presentation in systemic lupus erythematosus. Rheumatology (Oxford). [Internet]. Oxford University Press; 2013 [cited 2016 Aug 1];52:2108–15. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23641038 .

4. • Muñoz-Grajales C, González LA, Alarcón GS, Acosta-Reyes J. Gender differences in disease activity and clinical features in newly diagnosed systemic lupus erythematosus patients. Lupus [Internet]. 2016 [cited 2017 Nov 21];25:1217–23. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26921269 . This study found that in newly diagnosed SLE patients, male gender is associated with higher disease activity despite the fact that male and female patients seem to experience similar overall disease manifestations.

5. Garcia MA, Marcos JC, Marcos AI, Pons-Estel BA, Wojdyla D, Arturi A, et al. Male systemic lupus erythematosus in a Latin-American inception cohort of 1214 patients. Lupus [Internet]. 2005 [cited 2017 Nov 21];14:938–46. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16425573 .

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