1. American College of Rheumatology SubCommittee on Osteoarthritis Guidelines: Recommendations for the medical management of osteoarthritis of the hip and knee. Arthritis Rheum 2000, 43:9:1905–1915. This set of guidelines sponsored by the American College of Rheumatology provides a comprehensive background of nonpharmacologic and pharmacologic approaches to management. These guidelines are meant to be recommendations and not rigid approaches to management.
2. Reginster JY, Bruyere O, Henrotin Y: New perspectives in the management of osteoarthritis. Structure modification: facts or fantasy? J Rheumatol 2003, 30(Suppl_67):14–20. This review is an excellent assessment of current concepts of disease modification in osteoarthritis and commentary on state of the science of disease modification.
3. Abadie E, Ethgen D, Avouac B, et al.: Recommendations for the use of new methods to assess the efficacy of disease-modifying drugs in the treatment of osteoarthritis. Osteoarthritis Cartilage 2004, 12:263–268. This article reviews currently available methods to assess the effects of disease-modification drugs in the treatment of osteoarthritis. JSN on plain radiographs is considered the technique of choice at this time; MRI may provide significant advances in terms of evaluating whole organ structures.
4. Dougados M, Gueguen A, Nguyen M, et al.: Radiological progression of hip osteoarthritis: definition, risk factors and correlations with clinical status. Ann Rheum Dis 1996, 55:356–362.
5. Brandt KD, Mazucca SA, Conrozier T, et al.: What is the best radiographic protocol for clinical trial of a structure modifying drug in patients with osteoarthritis. J Rheumatol 2002, 29:1308–1320.