Phase I clinical and pharmacokinetic study of menogaril (7-con-O-methylnogarol) in previously treated patients with acute leukemia

Author:

Mazurek Constance,Dutcher Janice P.,Schwartz Edward L.,Garl Susan,Benson Laura,Wiernik Peter H.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Reference28 articles.

1. Bhuyan BK, Smith CG: Nogalamycin. In: Sartorelli AC and Johns DG, eds, Antineoplastic and Immunosuppressive Agents, Part 2, pp. 623?632. New York: Springer-Verlag, 1975

2. Neil GL, Kuentzel SL, McGovren JP: Treatment of mouse tumors with 7-con-O-methylnogarol and other analogs of the anthracycline antibiotic, nogalamycin. Cancer Treat Rep 63:1971?1978, 1979

3. Li LH, Kuentzel SL, Murch LL, Pschigoda LM, Krueger WG: Comparative biological and biochemical effects of nogalamycin and its analogs on L1210 leukemia. Cancer Res 39:4816?4822, 1979

4. Stewart DJ, Maroun JA, Verma S, Perrault D, Earhart RH: Phase I study of weekly intravenous administration of menogaril to adults with solid tumors. Am J Clin Oncol 12:511?518, 1989

5. McGovern JP, Nelson KD, Lassus M, Cradock JC, Plowman J, Cristopher JP: Menogaril: a new anthracycline agent entering clinical trials. Invest New Drugs 2:359?367, 1984

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