Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Reference21 articles.
1. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med. 1995;333:1581–7.
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3. Furlan AJ, Higashida R, Wechsler L, Gent M, Rowley H, Kase C, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. JAMA. 1999;282:2003–11.
4. •• The IST-3 Collaborative Group. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 hours of acute ischemic stroke (the third international stroke trial IST-3): a randomized controlled trial. Lancet. 2012. doi: 101016/S0140-6736(12)60768-5 . Published online, Largest randomized trial of IV tpa. No benefit of IV tpa at 6 hours from stroke onset based on primary endpoint.
5. •• IMS3 A Descriptive Study of Interventional Management of Stroke III Trial Investigator recruitment enhancement strategies. Stroke. 2012;43:A3192. Compares standard IV tpas < 3 hours to IV tpa plus IA intervention using 5 different IA techniques. Recently halted due to futility.
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