The Year Embolectomy Won: a Review of Five Trials Assessing the Efficacy of Mechanical Intervention in Acute Stroke
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11886-015-0657-x.pdf
Reference20 articles.
1. Stroke facts. http://www.cdc.gov/stroke/facts.htm “Stroke facts. 2015.
2. Mozaffarian D, Benjamin EJ, et al. Heart disease and stroke statistics–2015 update: a report from the American Heart Association. Circulation. 2015;131:e29–e322.
3. NINDS Study group. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581–7.
4. Berkhemer OA, Fransen PS, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015;372:11–20. This study was the first of five trials to report better outcomes with tPA paired to endovascular treatment, it prompted early stoppage of the other four on going trials (MR CLEAN trial).
5. Campbell BC, Mitchell PJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015;372:1009–18. This trial showed that the use of perfusion imaging in patient selection for embolectomy after tPA can improve outcomes.(EXTEND-IA trial).
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