Is Intensive Blood Pressure Control Indicated in Older Patients with Hypertension?

Author:

Htay Thwe,Lane Mariela,Khanjani Narges,Arabi Mianroodi Aliasghar,Ream-Winnick Sarah

Publisher

Springer Science and Business Media LLC

Reference24 articles.

1. • Wright JT Jr, Williamson JD, Whelton PK, Snyder JK, Sink KM, Rocco MV, et al. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373(22):2103–16. https://doi.org/10.1056/NEJMoa1511939. This landmark trial provided evidence that changed current guidelines for hypertension.

2. •• Goldenberg J, Blumenthal RS, Cingolani O, Whelton SP. Guidance on approaching hypertension in patients over 80 years of age. 2021. https://www.acc.org/Latest-in-Cardiology/Articles/2021/11/11/13/58/Guidance-on-Approaching-HTN-in-Patients-Over-80-Years-of-Age#:~:text=The%20totality%20of%20data%20suggests,more%20frequent%20monitoring%20is%20key. This expert analysis discusses finding interpretations of many trials and analyses regarding intensive BP goals in patient aged 80 years or older.

3. Aronow WS, Fleg JL, Pepine CJ, Artinian NT, Bakris G, Brown AS, et al. ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Circulation. 2011;123(21):2434–506. https://doi.org/10.1161/CIR.0b013e31821daaf6.

4. • Pajewski NM, Berlowitz DR, Bress AP, Callahan KE, Cheung AK, Fine LJ, et al. Intensive vs Standard Blood Pressure Control in Adults 80 Years or Older: A Secondary Analysis of the Systolic Blood Pressure Intervention Trial. J Am Geriatr Soc. 2020;68(3):496–504. https://doi.org/10.1111/jgs.16272. This secondary analysis provides more support for blood pressure management in adults aged 80 years or older.

5. •• Zhang W, Zhang S, Deng Y, Wu S, Ren J, Sun G, et al. Trial of intensive blood-pressure control in older patients with hypertension. N Engl J Med. 2021;385(14):1268–79. https://doi.org/10.1056/NEJMoa2111437. This recent multicenter, randomized controlled trial provides further evidence for intensive blood pressure control and its cardiovascular benefits for adults 60 to 80 years of age with hypertension.

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