Does the ISCHEMIA Trial Apply to My Patients?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
https://link.springer.com/content/pdf/10.1007/s11886-022-01684-7.pdf
Reference26 articles.
1. •• Maron DJ, Hochman JS, Reynolds HR, et al. Initial invasive or conservative strategy for stable coronary disease. N Engl J Med. 2020;382(15):1395–407. https://doi.org/10.1056/NEJMoa1915922. Findings of this study revealed that death from cardiovascular causes, including myocardial infarctions, hospitalizations related to cardiovascular events, or cardiac arrest were not reduced with initial invasive strategy in patients with stable ischemic heart disease and moderate or severe ischemia when compared to initial conservative medical management strategy.
2. Hochman JS, Reynolds HR, Bangalore S, et al. Baseline characteristics and risk profiles of participants in the ISCHEMIA randomized clinical trial [published correction appears in JAMA Cardiol. 2019 May 1;4(5):497]. JAMA Cardiol. 2019;4(3):273–86. https://doi.org/10.1001/jamacardio.2019.0014.
3. •• Spertus JA, Jones PG, Maron DJ, et al. Health-status outcomes with invasive or conservative care in coronary disease. N Engl J Med. 2020;382(15):1408–19. https://doi.org/10.1056/NEJMoa1916370. This study showed that based on the Seattle Angina Questionnaire, patients with stable ischemic heart disease and moderate or severe ischemia randomly assigned to invasive management for coronary artery disease versus medical management experienced greater improvement in their anginal symptoms.
4. Boden WE, Bhatt DL. Translating the findings of ISCHEMIA into clinical practice: a challenging START. EuroIntervention. 2020;16(12):e953-56. Published 2020 Dec 18. https://doi.org/10.4244/EIJV16I12A174.
5. Pijls NH, van Schaardenburgh P, Manoharan G, et al. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study. J Am Coll Cardiol. 2007;49(21):2105–11. https://doi.org/10.1016/j.jacc.2007.01.087.
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