Will Factor XI Inhibitors Replace Current Anticoagulants for Stroke Prevention in Atrial Fibrillation?

Author:

Patel Siddharth M.,Ruff Christian T.

Funder

National Heart, Lung, and Blood Institute

Publisher

Springer Science and Business Media LLC

Reference34 articles.

1. Elliott AD, Middeldorp ME, Van Gelder IC, Albert CM, Sanders P. Epidemiology and modifiable risk factors for atrial fibrillation. Nat Rev Cardiol. 2023;20:404–17. https://doi.org/10.1038/s41569-022-00820-8.

2. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22:983–8. https://doi.org/10.1161/01.STR.22.8.983.

3. Hart RG, Pearce LA, Aguilar MI. Meta-analysis: Antithrombotic Therapy to prevent stroke in patients who have Nonvalvular Atrial Fibrillation. Ann Intern Med. 2007;146:857–67. https://doi.org/10.7326/0003-4819-146-12-200706190-00007.

4. Joglar JA, Chung MK, Armbruster AL, Benjamin EJ, Chyou JY, Cronin EM, et al. 2023 ACC/AHA/ACCP/HRS Guideline for the diagnosis and management of Atrial Fibrillation: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice guidelines. Circulation. 2024;149:e1–156. https://doi.org/10.1161/CIR.0000000000001193.

5. Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomström-Lundqvist C, et al. 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): the Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Eur Heart J. 2021;42:373–498. https://doi.org/10.1093/eurheartj/ehaa612.

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