Importance of Residual Myocardial Ischemia After Intervention in the Genesis of Cardiovascular Events Among Patients with Chronic Coronary Artery Disease

Author:

Shaw Leslee J.,Hachamovitch Rory,Min James,Berman Daniel S.

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine

Reference29 articles.

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2. Frye RL, August P, Brooks MM, Hardison RM, Kelsey SF, MacGregor JM, et al. A randomized trial of therapies for type 2 diabetes and coronary artery disease. N Engl J Med. 2009;360:2503–15.

3. • Shaw LJ, Berman DS, Maron DJ, Mancini GB, Hayes SW, Hartigan PM, Weintraub WS, O’Rourke RA, Dada M, Spertus JA, Chaitman BR, Friedman J, Slomka P, Heller GV, Germano G, Gosselin G, Berger P, Kostuk WJ, Schwartz RG, Knudtson M, Veledar E, Bates ER, McCallister B, Teo KK, Boden WE. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: Results from the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial nuclear substudy. Circulation. 2008;117:1283–1291. This paper reports the results from the COURAGE nuclear substudy in 314 patients who underwent serial testing for the purposes of defining the efficacy of randomized treatments for reducing ischemia. The results of this substudy reveal an advantage with PCI plus optimal medical therapy in terms of ischemia reduction when compared with optimal medical therapy alone.

4. Shaw LJ, Iskandrian AE. Prognostic value of gated myocardial perfusion spect. J Nucl Cardiol. 2004;11:171–85.

5. Berman DS, Hachamovitch R, Kiat H, Cohen I, Cabico JA, Wang FP, et al. Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: A basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol. 1995;26:639–47.

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