The orphan MRGPRF receptor is expressed in entero-endocrine cells of the human gut mucosa

Author:

Van Remoortel Samuel,Lambeets Lana,De Schepper Heiko,Timmermans Jean-PierreORCID

Funder

FWO

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Reference27 articles.

1. Aguilera-Lizarraga J, Florens MV, Van Brussel T, Clevers E, Van Oudenhove L, Lambrechts D, Wouters MM, Boeckxstaens GE (2019) Expression of immune-related genes in rectum and colon descendens of irritable bowel syndrome patients is unrelated to clinical symptoms. Neurogastro Motil 31(6). https://doi.org/10.1111/nmo.13579

2. Al Hamwi G, Riedel YK, Clemens S, Namasivayam V, Thimm D, Müller CE (2022) MAS-related g protein-coupled receptors X (MRGPRX): orphan GPCRs with potential as targets for future drugs. Pharmacol Ther 238:108259. https://doi.org/10.1016/J.PHARMTHERA.2022.108259

3. Avula LR, Buckinx R, Alpaerts K, Costagliola A, Adriaensen D, Van Nassauw L, Timmermans JP (2011) The effect of inflammation on the expression and distribution of the MAS-related gene receptors MrgE and MrgF in the murine ileum. Histochem Cell Biol 136(5):569–585. https://doi.org/10.1007/s00418-011-0862-7

4. Avula LR, Buckinx R, Favoreel H, Cox E, Adriaensen D, Van Nassauw L, Timmermans J-P (2013) Expression and distribution patterns of mas-related gene receptor subtypes A-H in the mouse intestine: inflammation-induced changes. Histochem Cell Biol 139(5):639–658. https://doi.org/10.1007/s00418-013-1086-9

5. Bautzova T, Hockley JR, Perez-Berezo T, Pujo J, Tranter MM, Desormeaux C, Barbaro MR (2018) 5-OxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein–coupled receptor D. Sci Signal 11 11(561):eaal2171. https://doi.org/10.1126/scisignal.aal2171

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