The sympathies of the body: functional organization and neuronal differentiation in the peripheral sympathetic nervous system

Author:

Ernsberger Uwe,Deller Thomas,Rohrer HermannORCID

Abstract

AbstractDuring the last 30 years, our understanding of the development and diversification of postganglionic sympathetic neurons has dramatically increased. In parallel, the list of target structures has been critically extended from the cardiovascular system and selected glandular structures to metabolically relevant tissues such as white and brown adipose tissue, lymphoid tissues, bone, and bone marrow. A critical question now emerges for the integration of the diverse sympathetic neuron classes into neural circuits specific for these different target tissues to achieve the homeostatic regulation of the physiological ends affected.

Funder

wilhelm sander-stiftung

gemeinnützige hertie-stiftung

Johann Wolfgang Goethe-Universität, Frankfurt am Main

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

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